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KMID : 0366220110460010052
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Korean Journal of Hematology
2011 Volume.46 No. 1 p.52 ~ p.56
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Promyelocytic sarcoma of the sternum: a case report and review of the literature
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Thomas Xavier
Chelghoum Youcef
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Abstract
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This study reports a case of promyelocytic sarcoma that developed as a solitary sternal mass without any clinical evidence of acute promyelocytic leukemia. The case presented the diagnostic difficulties common to all aleukemic granulocytic sarcomas, and diagnosis was made possible by local identification of the PML/RARa fusion gene by fluorescent in situ hybridization. The patient was treated by surgery followed by chemotherapy plus all-trans retinoic acid therapy and local radiotherapy.
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KEYWORD
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Promyelocytic sarcoma, PML/RARa fusion, Acute promyelocytic leukemia
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